Production. Quality

A small family business "Yaroshenko & Co. Ltd." is engaged in manufacturing and sale of Pure Mumiye "Altai" in tablets over 15 years. The Company has got a lot of theoretical material about Mumiye properties and administration as well as an invaluable work experience with such a complicated and capricious natural product. The manufacturing of Mumiye tablets from pure raw Mumiye without introduction of all the possible additives is a labor-intensive process with employment of manual labor. The first idea appearing in this case is the wish to automatize the whole manufacturing process. The idea took us to the Novosibirsk Medical Preparations Plant in 1997, where we tried to manufacture tablets from the powder made of raw Mumiye together with the manufacturing chemists of the Plant. However, this attempt failed, because the manufacturing machine was brought out of operation for a month. We had to introduce additives and then it worked out well. To understand the situation better, we need to tell about tabletization from the manufacturing point of view.

Tablets Classification

The tablets are classified according to their method of production: compressed tablets and formed tablets. The first method of production is the primary one and typical almost for all manufactured tablets. The second method – formation – is the most time consuming and cost-intensive one. There are three main requirements imposed on tablets: 1) dose accuracy, 2) mechanical hardness and 3) disintegration or solubility. The mass exposed to the tabletization shall possess a complex of properties which could enable the fulfillment of these three requirements. If primary properties of basic substances are insufficiently effective, they shall be improved by adding of auxiliary substances or with the help of certain processing methods.

Auxiliary Substances and Fillers

Auxiliary substances give the necessary processing properties to the tabletized mass which provide tablets with dose accuracy, proper hardness and disintegration. There are the following auxiliary substances according to their indications: binding, antifriction and leavening substances. Their total quantity shall not exceed 20% of the basic substance mass. Fillers are substances which will be introduced into tablets (except for auxiliary substances) as a medium (carrier excipient) for primary substances included in small quantities. Binding substances: starch, ultrapentyne, polyvinyl alcohol (PVA), sodium (NMC), carboxymethylcel cellulose (CMC), methyl cellulose (MC), polyvinyl pyrrolidone (PVP). Antifriction substances: talc, starch, bentonites, aerosol. Talc and bentonites are added in amount of max. 3%, because they have an irritant action on mucosae. Lubricating substances: fatty acids and their salts (stearic acid, magnesium stearate, calcium stearate), hydrocarbons (liquid paraffin) and some high-molecular compounds (Tween-80, PEG 4000), which quantity shall not exceed 1%. The lubricating substances decrease friction on bounding areas of machine-tool equipment. Leavening substances: pectin, gelatin, starch, alginates, bentonites. Fillers: sodium chloride, sodium carbonate, starch.

General Manufacturing Operations

Materials preparation for tabletization

Majority of tabletized substances needs a special preparation – material granulation or graining. When granulating, there will be added some adhesive substances (for example, microcrystalline cellulose, polyethylene oxide), enabling pressurized particles adhesion both of hydrophilic and hydrophobic substances. The necessary quantity of lubricants (antifriction substances) shall be added to the granules before introducing it in the tableting machine.

Tabletization (compression)

Process consists of the following operations: - loading operation; - compressing operation; and - extrusion operation.

Filling and packaging are performed on special blister packaging machines.

Thus, we can draw a conclusion that the external application of compressed tablets is forbidden. The oral use of the tablets is also doubtful because the quantity of the basic substance (raw Mumiye) in the tablet is not clear. The manufacturers of compressed tablets deceive customers when they write “100% pure Mumiye” on the labels.

Our method of production belongs to the second variant, i.e. to the formation. At the same time, tablet manufacturing from Mumiye has a lot of distinguishing features. Therefore, the specialists of our enterprise developed an own production method of Mumiye tablets without inert additives (Patent No. 2256461) in 2004, the main point of which consists in the fact that the tablets are made of raw Mumiye with the help of a special manually operated dosage devise in the strict standard (observed) temperature and humidity conditions. In a few words the method is as follows: 1) A small part will be separated from the total mass of raw Mumiye and rolled through the rolling press, as a result of which there is a plate of the necessary thickness. 2) A special sharp-edged tube dispenser cuts the Mumiye plate. Then the dispenser will be took out of the plate with the tablet of the necessary diameter formed inside it, and after that the tablet will be extruded with the help of a special device to the group blister or leak-proof bag. 3) After the filling, the group blister or bag will be sealed off.

At the present time, our Company is the only one in Russia manufacturing tablets according to the patented technology from the pure raw Mumiye.

Every customer shall be aware of the fact that drugstores sell Mumiye powder in form of tablets on the whole, that’s why the self-maintained determination of its quality is very important. The qualitative Mumiye is of black color with a peculiar bitter-resinous odor and bitter taste, it becomes soft and plastic when kneaded with warm hands and it will be dissolved in water easily and without sediments.

Dear customers, try to determine the Mumiye quality yourselves: take a tablet from the blister and try to break it in two parts. If the tablet is easy to break, it means that you have the Mumiye powder (in some cases this is the overburnt Mumiye with a peculiar odor, sometimes such tablets can fall to pieces). The color of the tablets varies from dark brown, sometimes with visible impregnations. Certain manufacturers add one of the vegetable oils for manufacturing purposes. The oil becomes rancid with time (The oil shelf life is much less than the Mumiye shelf life).

The composition of ingredients shall be specified on the label in all the cases.

The Certificate of State Registration is a binding document for all the Mumiye kinds independent from their filling. Each batch of Mumiye (in tablets, capsules or bags) shall be accompanied by the Safety and Quality Certificate issued on the basis of the Test protocol of the Accredited Laboratory. If you buy Mumiye for the first time or from an unknown manufacturer, ask for the document confirming the quality of the saleable product! You will find samples of such documents at our website.